Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622449 | 0.92 | TDP1 (0.42) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL9493036 | 0.87 | SPHK1 (0.39) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL620027 | 0.85 | TDP1 (0.50) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL15369202 | 0.84 | USP2 (0.51) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL6437780 | 0.84 | TDP1 (0.45) | SPHK1MAPTLMNATDP1 | |
| SCHEMBL8718578 | 0.82 | TRPV1 (0.35) | SPHK1TDP1TRPV1TRPA1 | |
| SCHEMBL429521 | 0.80 | MAPT (0.41) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL15970081 | 0.80 | MAPT (0.41) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL25004972 | 0.80 | MAPT (0.47) | SPHK1MAPTCYP2D6GMNNLMNA | |
| SCHEMBL4142740 | 0.80 | TDP1 (0.34) | TDP1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836251-B1 | STABILIZER COMPOSITION CONTAINING PHOSPHITE ESTERS | BAERLOCHER ITALIA S P A (IT) | 2011-02-09 | — | — | EP | disclosed |
| EP-1836251-A1 | STABILIZER COMPOSITION CONTAINING PHOSPHITE ESTERS | Baerlocher Italia S.p.A. (IT) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006066947-A1 | STABILIZER COMPOSITION CONTAINING PHOSPHITE ESTERS | BAERLOCHER ITALIA S.P.A. (IT) | 2006-06-29 | — | — | WO | disclosed |