Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 2/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | FABP3 | P05413 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252382 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11253613 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11029353 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11253619 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11249272 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11157427 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11220701 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11249269 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11253622 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM | |
| SCHEMBL11234047 | 1.00 | TDP1 (0.43) | TDP1MEN1KMT2ALMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346251-A | 4-Substituted-2-indanols | FMC CORPORATION (US) | 1982-08-24 | — | — | US | disclosed |
| US-4335252-A | A4-PHENYL-Z-INDANYL CYCLOPROPANE CARBOXYLATE | FMC CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4263319-A | CYCLOPROPYL ESTERS | FMC CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |