⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Chloride SCHEMBL1331156 | 0.88 | — | — | |
| Propane SCHEMBL28345415 | 0.72 | — | — | |
| Methylene Chloride SCHEMBL181202 | 0.72 | — | — | |
| Methylene Chloride SCHEMBL669175 | 0.72 | — | — | |
| Ethyl Chloride SCHEMBL1331389 | 0.72 | — | — | |
| Ethyl Chloride SCHEMBL1331853 | 0.72 | — | — | |
| Ethyl Chloride SCHEMBL1331994 | 0.72 | — | — | |
| Ethyl Chloride SCHEMBL20021 | 0.72 | — | — | |
| Ethyl Chloride SCHEMBL1127611 | 0.72 | — | — | |
| Ethyl Chloride SCHEMBL8872436 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4361557-A | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4311857-A | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4235892-A | AROMATIC ANTIBIOTICS | Schering Corporation, Patent Dept. (US) | 1980-11-25 | — | — | US | disclosed |