Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CAD | P27708 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL478268 | 0.83 | KDM4E (0.61) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL1289325 | 0.83 | KDM4E (0.61) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL478269 | 0.83 | KDM4E (0.61) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL377413 | 0.81 | KDM4E (0.65) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL13299210 | 0.81 | KDM4E (0.39) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL12807977 | 0.81 | KDM4E (0.65) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL435838 | 0.81 | KDM4E (0.65) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL12807815 | 0.81 | KDM4E (0.39) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL929856 | 0.81 | KDM4E (0.39) | NFKB1THPOBLMKDM4EMAPT | |
| SCHEMBL18209617 | 0.79 | KDM4E (0.38) | NFKB1THPOBLMKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57028041-A | — | — | None | — | — | JP | disclosed |
| JP-S5728041-A | 2-CARBAMOYLAMINO-3-SUBSTITUTED-PROPIONAMIDE AND ITS PREPARATION | MITSUBISHI CHEM IND LTD | 1982-02-15 | — | — | JP | disclosed |