⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668887 | 0.72 | — | — | |
| SCHEMBL2526540 | 0.67 | — | — | |
| SCHEMBL8468536 | 0.67 | — | — | |
| SCHEMBL3109116 | 0.67 | — | — | |
| SCHEMBL10869950 | 0.67 | — | — | |
| SCHEMBL3109471 | 0.65 | — | — | |
| SCHEMBL3940041 | 0.63 | — | — | |
| SCHEMBL7637960 | 0.63 | — | — | |
| SCHEMBL7637986 | 0.63 | — | — | |
| SCHEMBL3895876 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585538-B1 | NON-HYPERTENSIVE PEGYLATED HEMOGLOBINS AND METHODS OF PREPARATION THEREOF | EINSTEIN COLL MED (US) | 2011-02-09 | — | — | EP | disclosed |
| US-7501499-B2 | Modified hemoglobin and methods of making same | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-20060135753-A1 | Modified hemoglobin and methods of making same | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2006-06-22 | — | — | US | disclosed |