Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234808 | 0.85 | HCRTR2 (0.38) | DRD2DRD3HCRTR2ADRA2ACYP19A1 | |
| SCHEMBL11233338 | 0.85 | HCRTR2 (0.38) | DRD2DRD3HCRTR2ADRA2ACYP19A1 | |
| SCHEMBL10895156 | 0.85 | HCRTR2 (0.38) | DRD2DRD3HCRTR2ADRA2ACYP19A1 | |
| SCHEMBL11234799 | 0.85 | HCRTR2 (0.38) | DRD2DRD3HCRTR2ADRA2ACYP19A1 | |
| SCHEMBL11233337 | 0.85 | HCRTR2 (0.38) | DRD2DRD3HCRTR2ADRA2ACYP19A1 | |
| SCHEMBL11229640 | 0.82 | CYP19A1 (0.38) | ADRA2ACYP19A1 | |
| SCHEMBL11227623 | 0.82 | CYP19A1 (0.45) | DRD2DRD3HCRTR2CYP19A1 | |
| SCHEMBL11227708 | 0.82 | CYP19A1 (0.33) | HCRTR2CYP19A1 | |
| SCHEMBL11236680 | 0.82 | CYP19A1 (0.44) | DRD2DRD3CYP19A1 | |
| SCHEMBL11236303 | 0.81 | CYP19A1 (0.33) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | claimed |
| US-4342775-A | FOR USE AS ANTICOAGULANT AND REDUCING SERUM SHOLESTEROL OR SERUM TRIGLYCERIDES | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-08-03 | — | — | US | disclosed |