Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223541 | 1.00 | PLCG1 (0.57) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11218239 | 0.93 | PLCG1 (0.57) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11218238 | 0.93 | PLCG1 (0.57) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11228563 | 0.91 | PLCG1 (0.56) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11338427 | 0.91 | PLCG1 (0.55) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11226408 | 0.91 | PLCG1 (0.55) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11338430 | 0.91 | PLCG1 (0.55) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11226411 | 0.91 | PLCG1 (0.55) | PLCG1ELANECTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11222938 | 0.90 | PLCG1 (0.53) | PLCG1CTDSP1L3MBTL1ALDH1A1CYP2C9 | |
| SCHEMBL11222935 | 0.90 | PLCG1 (0.53) | PLCG1CTDSP1L3MBTL1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4299954-A | MICROBIOCIDES | ELI LILLY AND COMPANY (US) | 1981-11-10 | — | — | US | claimed |
| US-4334064-A | Cephalosporin vinyl halides | ELI LILLY AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4334063-A | Cephalosporin vinyl halides | ELI LILLY AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4299954-A | MICROBIOCIDES | ELI LILLY AND COMPANY (US) | 1981-11-10 | — | — | US | disclosed |