Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.81 |
| ▸ | HPGD | P15428 | 3/20 | 0.81 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.81 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.81 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.81 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.81 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 1/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223624 | 1.00 | TDP1 (0.81) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11222226 | 0.95 | TDP1 (0.76) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11523565 | 0.93 | TDP1 (0.81) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11523562 | 0.93 | TDP1 (0.81) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL9436226 | 0.91 | TDP1 (0.81) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11523392 | 0.91 | TDP1 (0.84) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11523395 | 0.91 | TDP1 (0.84) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11221201 | 0.90 | TDP1 (0.85) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11221206 | 0.90 | TDP1 (0.85) | TDP1MAPTNR1I2HPGDSLC22A6 | |
| SCHEMBL11517829 | 0.90 | TDP1 (0.73) | TDP1MAPTNR1I2HPGDSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323676-A | Process for preparing cephalosporins | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4308381-A | Cephem compounds | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4245088-A | Novel 3-acyloxymethyl-cephem compounds useful as intermediates for preparing cephalosporin antibiotics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-01-13 | — | — | US | disclosed |