Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28669210 | 0.94 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL30854793 | 0.90 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL20745132 | 0.90 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4410571 | 0.89 | TSHR (0.68) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29216883 | 0.88 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10870250 | 0.88 | TSHR (0.67) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28322142 | 0.87 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7997075 | 0.87 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29198318 | 0.87 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28424867 | 0.87 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339527-A | BIS/ACRYLOYLOXYALKYL/HYDROCARBYLDICARBOXYLATES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4230790-A | COMPRISING A PHOTOINITIATOR, A POLYMERIC BINDER, AND AN ACRYLIC ESTER OF A DICARBOXYLIC ACID AND A GLYCOL ACRYLATE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |