Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.80 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336680 | 1.00 | TSHR (0.80) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL28679639 | 0.97 | TSHR (0.74) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL2830555 | 0.95 | TSHR (0.71) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL28432695 | 0.95 | TSHR (0.71) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL2832317 | 0.93 | TSHR (0.69) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL10526650 | 0.93 | TSHR (0.69) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL6914198 | 0.93 | TSHR (0.69) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL12346282 | 0.93 | TSHR (0.69) | TSHRTHRBNAAAPOLBAPEX1 | |
| SCHEMBL1323804 | 0.93 | TSHR (0.69) | TSHRTHRBNAAAPOLBAPEX1 | |
| Iodide SCHEMBL28802515 | 0.92 | TSHR (0.67) | TSHRTHRBNAAAPOLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055728-A4 | HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE. | GOODRICH CO B F (US) | 1982-08-11 | — | — | EP | disclosed |
| EP-0055728-A1 | HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE | The B.F. GOODRICH Company (US) | 1982-07-14 | — | — | EP | disclosed |
| EP-0047009-A1 | Hydrophilic interpolymers of acrylic acid and an olefin or a styrene | The B.F. GOODRICH Company (US) | 1982-03-10 | — | — | EP | disclosed |
| WO-1982000147-A1 | HYDROPHILIC INTERPOLYMERS OF ACRYLIC ACID AND AN ACRYLATE | GOODRICH CO B F (US) | 1982-01-21 | — | — | WO | disclosed |