Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.53 |
| ▸ | TUBB | P07437 | 7/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122375 | 1.00 | EGFR (0.59) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324310 | 0.81 | EGFR (0.59) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324314 | 0.81 | EGFR (0.59) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324945 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324981 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324862 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324370 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324870 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324979 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA | |
| SCHEMBL1324371 | 0.80 | EGFR (0.58) | EGFRCYP1A1CYP1A2CYP1B1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379508-B9 | N-(ARYL)-2-ARYLETHENESULFONAMIDES AND THERAPEUTIC USES THEREOF | UNIV TEMPLE (US) | 2011-02-09 | — | — | EP | disclosed |
| US-6646009-B2 | Use against proliferative disorders including cancer, and as a radioprotective compound for normal cells from ionizing radiation | Temple University — Of Commonwealth System of Higher Education | 2003-11-11 | — | — | US | disclosed |