Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 8/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822489 | 0.78 | HCAR2 (0.43) | HCAR2PDE4D | |
| SCHEMBL11411101 | 0.77 | HCAR2 (0.65) | HCAR2HCAR3BIDMCL1BCL2L1 | |
| SCHEMBL4761870 | 0.75 | HCAR2 (0.44) | HCAR2HCAR3BIDMCL1BCL2L1 | |
| SCHEMBL11035220 | 0.75 | HCAR2 (0.46) | HCAR2HCAR3PDE4DBIDMCL1 | |
| SCHEMBL28137757 | 0.74 | DYRK1A (0.38) | HCAR2HCAR3MAPT | |
| SCHEMBL22637664 | 0.72 | HCAR2 (0.42) | HCAR2PDE4D | |
| SCHEMBL9115479 | 0.72 | HCAR2 (0.55) | HCAR2HCAR3BIDMCL1BCL2L1 | |
| SCHEMBL11365654 | 0.72 | HCAR2 (0.59) | HCAR2HCAR3BIDMCL1BCL2L1 | |
| SCHEMBL14989207 | 0.71 | BID (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL14989301 | 0.71 | BID (0.51) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074749-A2 | Substituted pyrazole herbicides | UNIROYAL, INC. (US) | 1983-03-23 | — | — | EP | disclosed |