Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | INMT | O95050 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728651 | 0.86 | BRD4 (0.36) | BRD4BRD2 | |
| SCHEMBL16582753 | 0.72 | CRBN (0.39) | KMT2ALMNA | |
| SCHEMBL1549719 | 0.70 | CRBN (0.40) | ALDH1A1 | |
| SCHEMBL761946 | 0.68 | GRIN1 (0.42) | BRD4BRD2INMTGRIN1GRIN2A | |
| SCHEMBL11862409 | 0.68 | CRBN (0.38) | — | |
| SCHEMBL11867517 | 0.68 | CRBN (0.38) | — | |
| SCHEMBL11861618 | 0.68 | CRBN (0.38) | — | |
| SCHEMBL11864393 | 0.68 | CRBN (0.38) | — | |
| Methylpyrrolidone SCHEMBL1255511 | 0.66 | BRD4 (1.00) | BRD4BRD2INMTMEN1MAPT | |
| Methylpyrrolidone SCHEMBL8055062 | 0.66 | BRD4 (1.00) | BRD4BRD2INMTMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57146761-A | — | — | None | — | — | JP | disclosed |
| JP-S57146761-A | AZEPINDIONE | MITSUBISHI CHEM IND LTD | 1982-09-10 | — | — | JP | disclosed |