Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509196 | 0.84 | GAA (0.65) | GAAKMT2AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL8249922 | 0.82 | KMT2A (0.71) | GAAKMT2AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL14773591 | 0.81 | TP53 (0.52) | GAAKMT2AKAT6AKDM4EALDH1A1 | |
| SCHEMBL3915805 | 0.81 | GAA (0.62) | GAAKMT2AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL13299628 | 0.81 | GAA (0.62) | GAAKMT2AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL7424942 | 0.81 | GAA (0.62) | GAAKMT2AHSD11B1ALDH1A1NPSR1 | |
| SCHEMBL2024141 | 0.80 | KMT2A (0.73) | GAAKMT2AHSD11B1ALDH1A1NPSR1 | |
| SCHEMBL6751981 | 0.79 | KMT2A (0.71) | GAAKMT2AHSD11B1ALDH1A1NPSR1 | |
| SCHEMBL6460146 | 0.78 | GAA (0.58) | GAAKMT2AHSD11B1KDM4EALDH1A1 | |
| SCHEMBL17443310 | 0.77 | GAA (0.60) | GAAKMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326066-A | Triazolyl coumarin compounds, processes for their preparation and their use as whiteners and laser dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1982-04-20 | — | — | US | disclosed |