Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.68 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27906704 | 0.89 | ACE (0.61) | ACE | |
| SCHEMBL27890162 | 0.89 | ACE (0.61) | ACE | |
| SCHEMBL27890165 | 0.86 | ACE (0.73) | ACELTA4H | |
| SCHEMBL27890164 | 0.86 | ACE (0.73) | ACELTA4H | |
| SCHEMBL10679400 | 0.85 | ACE (0.66) | ACE | |
| SCHEMBL27890168 | 0.85 | ACE (0.61) | ACE | |
| SCHEMBL27906706 | 0.85 | ACE (0.61) | ACE | |
| SCHEMBL28803852 | 0.83 | ACE (0.64) | ACELTA4H | |
| SCHEMBL10885166 | 0.83 | ACE (0.64) | ACE | |
| SCHEMBL17660482 | 0.83 | ACE (0.75) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079522-A1 | N-Carboxymethyl(amidino)lysyl-proline antihypertensive agents | MERCK & CO. INC. (US) | 1983-05-25 | — | — | EP | disclosed |