Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.37 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11225729 | 1.00 | PLCG1 (0.52) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11224879 | 0.93 | PLCG1 (0.51) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11224877 | 0.93 | PLCG1 (0.51) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11222938 | 0.92 | PLCG1 (0.53) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11222935 | 0.92 | PLCG1 (0.53) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11226408 | 0.92 | PLCG1 (0.55) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11226411 | 0.92 | PLCG1 (0.55) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11227030 | 0.85 | TDP1 (0.53) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11227032 | 0.85 | TDP1 (0.53) | PLCG1L3MBTL1TDP1CTDSP1ALDH1A1 | |
| SCHEMBL11260113 | 0.84 | PLCG1 (0.63) | PLCG1L3MBTL1CTDSP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4334064-A | Cephalosporin vinyl halides | ELI LILLY AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |
| US-4334063-A | Cephalosporin vinyl halides | ELI LILLY AND COMPANY (US) | 1982-06-08 | — | — | US | disclosed |