SCHEMBL1122600

SCHEMBL1122600

CCCCCCCC(=O)Oc1[nH]c2ccccc2c1I

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.46
GAA P10253 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HSD17B10 Q99714 3/20 0.46
HPGD P15428 2/20 0.46
GSK3B P49841 1/20 0.43
OXER1 Q8TDS5 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
MAPT P10636 1/20 0.41
CTSV O60911 1/20 0.41
CTSL P07711 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1121861 0.86 GAA (0.47) MGAMGAASIMGAM2KDM4E
SCHEMBL1121911 0.85 GAA (0.46) MGAMGAASIMGAM2KDM4E
SCHEMBL1122036 0.85 GAA (0.46) MGAMGAASIMGAM2KDM4E
SCHEMBL15558927 0.78 GAA (0.47) MGAMGAASIMGAM2KDM4E
SCHEMBL9397133 0.76 POLM (0.50) MGAMGAASIMGAM2KDM4E
SCHEMBL9398516 0.76 POLM (0.50) MGAMGAASIMGAM2KDM4E
SCHEMBL27864646 0.76 POLM (0.50) MGAMGAASIMGAM2KDM4E
SCHEMBL23271733 0.74 EPHX2 (0.51) KDM4ELMNASMN1; SMN2
SCHEMBL20398671 0.74 EPHX2 (0.51) KDM4ELMNASMN1; SMN2
SCHEMBL20398624 0.74 EPHX2 (0.51) KDM4ELMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US claimed
JP-4794627-B2 2011-10-19 JP claimed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP claimed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP claimed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US claimed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP claimed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO claimed
US-9328373-B2 Detection of Salmonella lactose+ RAMBACH ALAIN (FR) 2016-05-03 US disclosed
EP-1931796-B9 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-06-08 EP disclosed
EP-1931796-B1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2011-02-09 EP disclosed
US-20100297690-A1 Detection of salmonella lactose+ RAMBACH ALAIN 2010-11-25 US disclosed
EP-1931796-A1 DETECTION OF SALMONELLA LACTOSE+ Rambach, Alain (FR) 2008-06-18 EP disclosed
WO-2007023185-A1 DETECTION OF SALMONELLA LACTOSE+ RAMBACH ALAIN (FR) 2007-03-01 WO disclosed