Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661364 | 0.97 | PHGDH (0.44) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL11217455 | 0.94 | PHGDH (0.48) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL11223140 | 0.94 | PHGDH (0.48) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL10664308 | 0.94 | PHGDH (0.48) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL11226739 | 0.94 | PHGDH (0.48) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL2666160 | 0.71 | PHGDH (0.44) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL17710576 | 0.67 | PHGDH (0.40) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL1001644 | 0.65 | PHGDH (0.62) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL8179982 | 0.65 | PHGDH (0.44) | PHGDHALDH1A1ADH1CADH1A | |
| SCHEMBL3912450 | 0.65 | PHGDH (0.44) | PHGDHALDH1A1ADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342841-A | Polyamide polyurethane prepared by reaction of polyisocyanate with a 1,1-diamino ethylene | THE UPJOHN COMPANY (US) | 1982-08-03 | — | — | US | disclosed |
| US-4338428-A | Novel polyamides from ketene-aminals | THE UPJOHN COMPANY (US) | 1982-07-06 | — | — | US | disclosed |