Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228752 | 0.81 | CYP19A1 (0.52) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL10476950 | 0.80 | ALPG (0.58) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL29669830 | 0.78 | CA12 (0.56) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL11230081 | 0.78 | CYP11B1 (0.53) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL18788080 | 0.78 | CYP19A1 (0.52) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL10878611 | 0.78 | CA12 (0.56) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL11275825 | 0.76 | CYP11B1 (0.55) | CYP19A1HMOX2CYP11B1CYP11B2 | |
| SCHEMBL11276476 | 0.76 | POLB (0.55) | CYP19A1ALPIALPGTDP1PLAA | |
| Hydrochloric Acid SCHEMBL9996122 | 0.75 | POLB (0.54) | CYP19A1ALPIALPGTDP1PLAA | |
| SCHEMBL11231205 | 0.74 | CYP19A1 (0.67) | CYP19A1ALPIALPGTDP1PLAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |