Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904905 | 0.87 | KMT2A (0.53) | KMT2AMEN1GAAIDO1ALDH1A1 | |
| SCHEMBL11398722 | 0.81 | IDO1 (0.52) | KMT2AMEN1GAAIDO1ALDH1A1 | |
| SCHEMBL6689946 | 0.81 | IDO1 (0.67) | KMT2AMEN1GAAIDO1ALDH1A1 | |
| SCHEMBL21071801 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL21071450 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL21071617 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL21071615 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL21071669 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL21071449 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 | |
| SCHEMBL19852510 | 0.79 | GAA (0.67) | KMT2AMEN1GAAALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360464-A | Process for production of 1-aryloxy-aminopropane derivatives | TEIKOKU HORMONE MFG. CO. LTD. (JP) | 1982-11-23 | — | — | US | disclosed |
| EP-0003664-B1 | ALKANOLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | disclosed |
| US-4275058-A | 1-(7-METHYLINDAN-4-YLOXY)-3-ISOPROPYLAMINOBUTAN-2-OL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-06-23 | — | — | US | disclosed |
| EP-0003664-A1 | Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-08-22 | — | — | EP | disclosed |
| US-4018824-A | ANTIULCER AND ADRENERGIC BLOCKING AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1977-04-19 | — | — | US | disclosed |