SCHEMBL11228775

SCHEMBL11228775

NCCNCCNCCNCCS

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.74
CA12 O43570 5/20 0.69
CA6 P23280 5/20 0.69
CA7 P43166 5/20 0.69
CA9 Q16790 5/20 0.69
CA14 Q9ULX7 5/20 0.69
CA5B Q9Y2D0 5/20 0.69
LMNA P02545 4/20 0.69
TDP1 Q9NUW8 4/20 0.69
CA2 P00918 4/20 0.69
CA4 P22748 4/20 0.69
CA5A P35218 4/20 0.69
CA3 P07451 3/20 0.69
ALOX15 P16050 3/20 0.69
CA1 P00915 2/20 0.69
ALDH1A1 P00352 2/20 0.69
TP53 P04637 1/20 0.69
KDM4E B2RXH2 1/20 0.65
MEN1 O00255 2/20 0.62
RECQL P46063 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7524242 1.00 ESR1 (0.74) ESR1CA12CA6CA7CA9
SCHEMBL7757906 0.97
SCHEMBL17119217 0.91 ESR1 (0.79) ESR1CA12CA6CA7CA9
SCHEMBL22017445 0.85 CA12 (0.65) ESR1CA12CA6CA7CA9
Wr-1065 SCHEMBL38865 0.85
SCHEMBL25340653 0.83 CA12 (1.00) ESR1CA12CA6CA7CA9
Trientine SCHEMBL15439 0.83 CA12 (1.00) ESR1CA12CA6CA7CA9
Trientine SCHEMBL3840289 0.83 CA12 (1.00) ESR1CA12CA6CA7CA9
SCHEMBL25342922 0.83 CA12 (1.00) ESR1CA12CA6CA7CA9
SCHEMBL20985200 0.83 ESR1 (0.56) ESR1CA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315846-A FUNGICIDES TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-16 US disclosed
EP-0037861-A1 Salts of alkylenebisdithiocarbamic acid derivatives, processes for their preparation, fungicidal compositions containing them and methods of combating fungi TOKYO ORGANIC CHEMICAL INDUSTRIES, LTD. (JP) 1981-10-21 EP disclosed