Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9021254 | 0.89 | TAAR1 (0.45) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL8346410 | 0.89 | TAAR1 (0.61) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL9613957 | 0.89 | TAAR1 (0.45) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL3169926 | 0.89 | TAAR1 (0.45) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL5979175 | 0.86 | TAAR1 (0.46) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL10793624 | 0.86 | KDM4E (0.56) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL2094863 | 0.85 | SLC6A2 (0.47) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL9249000 | 0.85 | SLC6A2 (0.64) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL9021284 | 0.84 | SLC6A2 (0.46) | TAAR1SLC6A2HRH1HRH3SLC6A4 | |
| SCHEMBL9021024 | 0.82 | KCNH2 (0.45) | TAAR1SLC6A2HRH1HRH3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286493-A | Preparation method of 4,4' -diethoxybiphenyl | 北京格林凯默科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-4336267-A | Heart active compounds and methods of use | AKTIEBOLAGET HASSLE (SE) | 1982-06-22 | — | — | US | disclosed |
| US-4244969-A | (P-HYDROXYPHENOXY)PROPANOLAMINE DERIVATIVES USEFUL AS B-RECEPTOR STIMULANTS | AKTIEBOLAGET HASSLE (SE) | 1981-01-13 | — | — | US | disclosed |