Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229265 | 1.00 | MAPT (0.55) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Hydrochloric Acid SCHEMBL11769851 | 0.98 | MAPT (0.54) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Hydrochloric Acid SCHEMBL11769856 | 0.98 | MAPT (0.54) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Bromide SCHEMBL11775659 | 0.92 | MAPT (0.49) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Bromide SCHEMBL11775653 | 0.92 | MAPT (0.49) | MAPTKMT2ANPFFR2NPSR1POLB | |
| SCHEMBL13673614 | 0.92 | MAPT (0.51) | MAPTKMT2ANPFFR2NPSR1POLB | |
| SCHEMBL13673616 | 0.92 | MAPT (0.51) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Bromide SCHEMBL11772714 | 0.90 | MAPT (0.50) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Hydrochloric Acid SCHEMBL11772915 | 0.90 | MAPT (0.50) | MAPTKMT2ANPFFR2NPSR1POLB | |
| Bromide SCHEMBL11772707 | 0.90 | MAPT (0.50) | MAPTKMT2ANPFFR2NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310541-A | WITH A BIS(BENZYLIDENEAMINO)GUANIDINE | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | claimed |
| US-4310541-A | WITH A BIS(BENZYLIDENEAMINO)GUANIDINE | MERCK & CO., INC. (US) | 1982-01-12 | — | — | US | disclosed |