Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.63 |
| ▸ | SCN1A | P35498 | 3/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.63 |
| ▸ | HRH1 | P35367 | 6/20 | 0.61 |
| ▸ | HTR2A | P28223 | 5/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | THPO | P40225 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11226344 | 0.98 | CHRM2 (0.61) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL11228116 | 0.87 | HRH1 (0.63) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL11230021 | 0.87 | CHRM2 (0.48) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL10956049 | 0.86 | HRH1 (0.56) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL11233845 | 0.85 | CHRM2 (0.47) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL11225540 | 0.84 | CHRM2 (0.46) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL11238126 | 0.84 | CHRM2 (0.46) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL953334 | 0.84 | CHRM2 (0.43) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL954734 | 0.83 | CHRM2 (0.45) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL11223097 | 0.83 | SLC6A4 (0.45) | CHRM2SLC6A2SLC6A4SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324792-A | SKIN DISORDERS, HAY FEVER, ASTHMA | GLAXO GROUP LIMITED (GB) | 1982-04-13 | — | — | US | claimed |
| US-4324792-A | SKIN DISORDERS, HAY FEVER, ASTHMA | GLAXO GROUP LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |