SCHEMBL11229599

SCHEMBL11229599

ClCS(CCl)(Cc1ccc(Cl)cc1Cl)SCc1ccsc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 2/20 0.40
IDO1 P14902 6/20 0.36
HTT P42858 3/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.33
CYP19A1 P11511 1/20 0.33
NR1I2 O75469 1/20 0.33
NR3C1 P04150 1/20 0.33
CYP17A1 P05093 1/20 0.33
PGR P06401 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11229601 0.76 CYP1A2 (0.61) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL6732304 0.65 IDO1 (0.42) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL3672833 0.62 ERCC1 (0.51) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL1648141 0.62 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL1625791 0.62 IDO1 (0.54) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL11353946 0.62 CYP1A2 (0.69) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL11230158 0.62 CYP1A2 (0.33) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL5615559 0.61 ERCC1 (0.50) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL4863737 0.61 CYP1A2 (1.00) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19
SCHEMBL271766 0.60 IDO1 (0.52) CYP1A2CYP3A4CYP2C9MAPK1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315023-A FOR USE AS FUNGICIDES AND BACTERICIDES WESTWOOD PHARMACEUTICALS, INC. (US) 1982-02-09 US disclosed