Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11223157 | 0.88 | CA1 (0.49) | MAPTHDAC1FBP1CYP19A1CA1 | |
| SCHEMBL10431528 | 0.86 | CA12 (0.51) | HDAC6CA1CA2 | |
| SCHEMBL11233290 | 0.86 | MEN1 (0.52) | MAPTMEN1HTTKMT2A | |
| SCHEMBL11230387 | 0.85 | MAPT (0.53) | MAPTHDAC3HDAC1HDAC2HDAC6 | |
| Ammonia Solution, Strong SCHEMBL10582019 | 0.85 | CA12 (0.50) | HDAC6CA1CA2 | |
| SCHEMBL11222945 | 0.84 | FFAR1 (0.51) | HDAC6CYP19A1 | |
| SCHEMBL29509788 | 0.83 | HDAC8 (0.54) | HDAC6HTR6CA1CA2HTT | |
| SCHEMBL10431526 | 0.83 | HDAC8 (0.54) | HDAC6HTR6CA1CA2HTT | |
| SCHEMBL6700054 | 0.82 | CHRM2 (0.55) | MAPTHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL632217 | 0.82 | CHRM2 (0.55) | MAPTHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328244-A | ANTIVIRAL AGENT | THE DOW CHEMICAL COMPANY (US) | 1982-05-04 | — | — | US | disclosed |