Methacrylic Acid

Methacrylic Acid

SCHEMBL11230462

C=C(C)C(=O)O.C=C(C)C(=O)O.CCCCC(CC)COC(=O)C(C)=CCC(C)C

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.49
CYP3A4 P08684 4/20 0.45
TDP1 Q9NUW8 2/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 5/20 0.41
LMNA P02545 3/20 0.41
MAPK1 P28482 3/20 0.41
CA2 P00918 3/20 0.40
RECQL P46063 1/20 0.39
HSD17B10 Q99714 1/20 0.37
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
MMP14 P50281 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL27427055 0.86 TSHR (0.45) TSHRCYP3A4TDP1ATMALDH1A1
Methacrylic Acid SCHEMBL28292362 0.85 TSHR (0.49) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL29752810 0.84 TSHR (0.50) TSHRCYP3A4TDP1ATMALDH1A1
Methacrylic Acid SCHEMBL4447127 0.83 TSHR (0.56) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL9576398 0.82 TSHR (0.46) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL28283091 0.80 TSHR (0.56) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL27085771 0.79 TSHR (0.52) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL6426749 0.79 TSHR (0.50) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL14660235 0.79 TSHR (0.55) TSHRCYP3A4TDP1ATMALDH1A1
SCHEMBL15415119 0.79 TSHR (0.64) TSHRCYP3A4TDP1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323600-A THERMOSETTING VINYL COPOLYMER UNDERCOATING CONTAINING PIGMENT BAKED WITH A CLEAR OVERCOATING MITSUI TOATSU CHEMICALS, INC. (JP) 1982-04-06 US disclosed