Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230784 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11238378 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL6954138 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11238381 | 0.92 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11231147 | 0.91 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11231142 | 0.91 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11230738 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11230741 | 0.89 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11228463 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1CYP2C19MEN1 | |
| SCHEMBL11239245 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2RAB9ANPC1CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |