Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.69 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936603 | 0.85 | SMPD1 (0.56) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL5936626 | 0.83 | BRD4 (0.60) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL11549645 | 0.83 | BRD4 (0.70) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL38660185 | 0.83 | BRD4 (0.70) | HDAC1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL38659760 | 0.81 | MEN1 (0.62) | HDAC1HDAC8HDAC6ALDH1A1TSHR | |
| SCHEMBL7713160 | 0.80 | SMPD1 (0.64) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL7049305 | 0.80 | SMPD1 (0.60) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL7076463 | 0.79 | SMPD1 (0.52) | SMPD1NR1H4HDAC1HDAC8HDAC6 | |
| SCHEMBL38660966 | 0.79 | MEN1 (0.60) | ALDH1A1MEN1KMT2ABRD4MRGPRX4 | |
| SCHEMBL7710629 | 0.79 | KDM4E (0.66) | SMPD1NR1H4HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | claimed |