Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 8/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.45 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239862 | 0.96 | KCNH2 (0.84) | KCNH2MAPTTSHRALDH1A1 | |
| SCHEMBL11233411 | 0.92 | KCNH2 (0.89) | KCNH2MAPTTSHRALDH1A1 | |
| SCHEMBL11230241 | 0.92 | KCNH2 (0.89) | KCNH2MAPTTSHRALDH1A1 | |
| SCHEMBL11230164 | 0.92 | KCNH2 (0.89) | KCNH2MAPTTSHRALDH1A1 | |
| SCHEMBL11221493 | 0.92 | KCNH2 (0.89) | KCNH2MAPTTSHRALDH1A1 | |
| Bromide SCHEMBL11235494 | 0.91 | KCNH2 (0.86) | KCNH2MAPTTSHRALDH1A1 | |
| SCHEMBL11242679 | 0.91 | KCNH2 (0.86) | KCNH2MAPTTSHRALDH1A1 | |
| Oxalic Acid SCHEMBL11238467 | 0.89 | KCNH2 (0.74) | KCNH2ALDH1A1 | |
| Oxalic Acid SCHEMBL11229293 | 0.89 | KCNH2 (0.74) | KCNH2ALDH1A1 | |
| Oxalic Acid SCHEMBL11238473 | 0.89 | KCNH2 (0.74) | KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336269-A | ANTIARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |