Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228752 | 0.82 | CYP19A1 (0.52) | KDM4EAHRNPSR1CYP19A1 | |
| SCHEMBL29669830 | 0.77 | CA12 (0.56) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10878611 | 0.77 | CA12 (0.56) | CA12CA1CA2CA3CA4 | |
| SCHEMBL12045387 | 0.71 | CA12 (0.55) | CA12CA1CA2CA3CA4 | |
| Hydrochloric Acid SCHEMBL9996095 | 0.70 | CA12 (0.54) | CA12CA1CA2CA3CA4 | |
| Hydrochloric Acid SCHEMBL10507465 | 0.70 | CYP19A1 (0.52) | CA12CA1CA2CA3CA4 | |
| SCHEMBL10476950 | 0.68 | ALPG (0.58) | CA12CA1CA2CA3CA4 | |
| Hydrochloric Acid SCHEMBL11465178 | 0.68 | CA12 (0.55) | CA12CA1CA2CA3CA4 | |
| SCHEMBL6151343 | 0.68 | ALPG (0.51) | CA12CA1CA2CA3CA4 | |
| SCHEMBL11276476 | 0.68 | POLB (0.55) | KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |