Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240200 | 1.00 | KCNH2 (0.71) | KCNH2ALDH1A1MAPTTSHRTHRA | |
| SCHEMBL28042131 | 0.89 | KCNH2 (0.60) | KCNH2ALDH1A1MAPTMGLL | |
| SCHEMBL11221493 | 0.86 | KCNH2 (0.89) | KCNH2ALDH1A1MAPTTSHRTHRA | |
| SCHEMBL11230164 | 0.86 | KCNH2 (0.89) | KCNH2ALDH1A1MAPTTSHRTHRA | |
| SCHEMBL11230241 | 0.86 | KCNH2 (0.89) | KCNH2ALDH1A1MAPTTSHRTHRA | |
| SCHEMBL11233411 | 0.86 | KCNH2 (0.89) | KCNH2ALDH1A1MAPTTSHRTHRA | |
| SCHEMBL25174460 | 0.85 | KCNH2 (0.77) | KCNH2ALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL1881781 | 0.85 | KCNH2 (0.77) | KCNH2ALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL8743949 | 0.85 | KCNH2 (0.77) | KCNH2ALDH1A1MAPTTSHRMEN1 | |
| SCHEMBL4190401 | 0.85 | KCNH2 (0.77) | KCNH2ALDH1A1MAPTTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336269-A | ANTIARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4277501-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |