Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | PYGL | P06737 | 4/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.46 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240787 | 0.94 | GCGR (0.53) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL11245158 | 0.86 | GCGR (0.54) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL11244889 | 0.86 | TDP1 (0.52) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL11237757 | 0.84 | MEN1 (0.49) | NPC1RAB9APOLBPKMTDP1 | |
| SCHEMBL11245400 | 0.81 | GCGR (0.60) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL11236694 | 0.80 | GCGR (0.52) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL8840342 | 0.78 | NPC1 (0.60) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL11245409 | 0.78 | MEN1 (0.47) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL11242785 | 0.78 | TDP1 (0.51) | NPC1RAB9APOLBPKMPYGL | |
| SCHEMBL10617761 | 0.77 | NPC1 (0.59) | NPC1RAB9APOLBPKMPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350706-A | MITICIDES, LARVICIDES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1982-09-21 | — | — | US | disclosed |