Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11717123 | 0.89 | TSHR (0.58) | SMN1; SMN2MAPTTSHRCYP1A2CYP2C9 | |
| SCHEMBL10022853 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL13147651 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL15797706 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL11716051 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL10874945 | 0.81 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL10729791 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL11781765 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL27877003 | 0.79 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTHPGDTSHRCYP1A2 | |
| SCHEMBL11722064 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2HPGDTSHRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348534-A | Preparation of 2-aryloxy-2-haloproptonic acid compounds | BASF AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4056628-A | Insecticidal esters of alpha-phenoxy alkanoic acids with substituted benzyl alcohols | HOFFMANN-LA ROCHE INC. (US) | 1977-11-01 | — | — | US | disclosed |