Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHAT | P28329 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL2150148 | 0.90 | HDAC8 (0.40) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL80079 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL968499 | 0.85 | — | — | |
| Bromide SCHEMBL1502845 | 0.85 | — | — | |
| Iodide SCHEMBL1165260 | 0.85 | — | — | |
| Water SCHEMBL2150329 | 0.85 | — | — | |
| SCHEMBL2150256 | 0.78 | SLC22A2 (0.46) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| SCHEMBL28677900 | 0.78 | HDAC8 (0.43) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Acetic Acid SCHEMBL30212895 | 0.77 | USP2 (0.41) | HDAC8SLC22A2SLC22A1SLC22A3SLC6A4 | |
| Sulfuric Acid SCHEMBL4280131 | 0.75 | GAA (0.41) | HDAC8SLC6A4KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318981-A | Homogeneous specific binding assay employing an intramolecularly modulated photogenic enzyme substrate label | MILES LABORATORIES, INC. (US) | 1982-03-09 | — | — | US | disclosed |