Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725874 | 0.74 | KMT2A (0.63) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL13819800 | 0.74 | KMT2A (0.42) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL14302656 | 0.74 | KMT2A (0.42) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL31611980 | 0.74 | KMT2A (0.42) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL10438960 | 0.67 | KMT2A (0.48) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL3583079 | 0.66 | IDO1 (0.38) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL22541269 | 0.64 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL21578365 | 0.63 | SETD7 (0.47) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL3402653 | 0.63 | NOTUM (0.48) | SMN1; SMN2NPC1RAB9AMAPTKMT2A | |
| SCHEMBL29690426 | 0.63 | NOTUM (0.48) | SMN1; SMN2NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339081-B1 | ANTIBACTERIAL ACTIVITY | AVECIA LIMITED (GB) | 2002-01-15 | — | — | US | claimed |
| EP-0946097-B1 | COMPOSITION AND USE | AVECIA LTD (GB) | 2001-05-02 | — | — | EP | claimed |
| EP-0946097-A1 | COMPOSITION AND USE | ZENECA LIMITED (GB) | 1999-10-06 | — | — | EP | claimed |
| WO-1999045975-A1 | NON-WOVEN MATERIAL COMPRISING CYCLIC THIOHYDROXAMIC ACID | AVECIA LIMITED (GB) | 1999-09-16 | — | — | WO | claimed |
| WO-1998026665-A1 | COMPOSITION AND USE | ZENECA LIMITED (GB) | 1998-06-25 | — | — | WO | claimed |
| US-5506253-A | REACTING ACETOXYPYRROLIDINONE COMPOUND WITH METAL TRIALKYLSILANOLATE | ZENECA LIMITED (GB) | 1996-04-09 | — | — | US | claimed |
| US-5500217-A | MICROBIOCIDE FOR COSMETICS | ZENECA LIMITED (GB) | 1996-03-19 | — | — | US | claimed |
| EP-0498636-B1 | Cosmetic composition | ZENECA LTD (GB) | 1995-09-06 | — | — | EP | claimed |
| US-5393750-A | Biocides | ZENECA, LIMITED (GB) | 1995-02-28 | — | — | US | claimed |
| WO-1992013520-A1 | COMPOSITION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-20 | — | — | WO | claimed |
| EP-0498636-A1 | Cosmetic composition | ZENECA LIMITED (GB) | 1992-08-12 | — | — | EP | claimed |
| US-5120856-A | Bactericides, fungicides, algicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-09 | — | — | US | claimed |
| EP-0409617-A2 | Thiolactams, process for their preparation and use as biocides | ZENECA LIMITED (GB) | 1991-01-23 | — | — | EP | claimed |
| US-8603453-B2 | Antimicrobial polymeric biguanide and acidic co-polymer composition and method of use | ARCH UK BIOCIDES LIMITED (GB) | 2013-12-10 | — | — | US | disclosed |
| EP-1624754-B1 | ANTIMICROBIAL COMPOSITION CONTAINING A POLYMERIC BIGUANIDE AND A COPOLYMER AND USE THEREOF | ARCH UK BIOCIDES LTD (GB) | 2011-02-09 | — | — | EP | disclosed |
| US-7851541-B2 | Composition and use | ARCH UK BIOCIDES LIMITED (GB) | 2010-12-14 | — | — | US | disclosed |
| WO-1992013520-A1 | COMPOSITION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-20 | — | — | WO | disclosed |
| EP-0498636-A1 | Cosmetic composition | ZENECA LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |
| US-5120856-A | Bactericides, fungicides, algicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-06-09 | — | — | US | disclosed |
| EP-0409617-A2 | Thiolactams, process for their preparation and use as biocides | ZENECA LIMITED (GB) | 1991-01-23 | — | — | EP | disclosed |