Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 3/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.50 |
| ▸ | CTSC | P53634 | 2/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | XIAP | P98170 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27183297 | 1.00 | NPC1 (0.61) | NPC1RAB9ALMNALTA4HTAAR1 | |
| SCHEMBL30573673 | 0.89 | NPC1 (0.67) | NPC1RAB9ALMNALTA4HTAAR1 | |
| SCHEMBL10135745 | 0.89 | NPC1 (0.67) | NPC1RAB9ALMNALTA4HTAAR1 | |
| SCHEMBL970530 | 0.89 | NPC1 (0.67) | NPC1RAB9ALMNALTA4HTAAR1 | |
| SCHEMBL27183419 | 0.88 | SLC7A5 (0.51) | NPC1RAB9ATAAR1SLC7A5 | |
| SCHEMBL27183078 | 0.87 | MME (0.46) | NPC1RAB9ALMNALTA4HKMT2A | |
| SCHEMBL24931056 | 0.86 | NPC1 (0.63) | NPC1RAB9ALMNATAAR1CTRB1 | |
| SCHEMBL974013 | 0.86 | NPC1 (0.63) | NPC1RAB9ALMNATAAR1CTRB1 | |
| SCHEMBL10195699 | 0.86 | NPC1 (0.63) | NPC1RAB9ALMNATAAR1CTRB1 | |
| SCHEMBL11707520 | 0.85 | SMN1; SMN2 (0.58) | NPC1RAB9ACTSCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338346-A | Non-nutritive sweetener | THE PROCTER & GAMBLE COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| EP-0013044-A1 | L-aspartyl amide derivatives and their use as sweetening agents | THE PROCTER & GAMBLE COMPANY (US) | 1980-07-09 | — | — | EP | disclosed |