Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381050 | 0.88 | KDM4E (0.51) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL11245243 | 0.86 | KDM4E (0.52) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL6562559 | 0.86 | KDM4E (0.54) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL11228906 | 0.83 | KDM4E (0.51) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL10769714 | 0.82 | KDM4E (0.57) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL10766144 | 0.82 | KDM4E (0.57) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL17949841 | 0.82 | KDM4E (0.60) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL10768477 | 0.81 | KDM4E (0.56) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL7893080 | 0.80 | KDM4E (0.48) | KDM4EUSP2LMNAKMT2AMEN1 | |
| SCHEMBL14419047 | 0.79 | KDM4E (0.69) | KDM4EUSP2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4327018-A | Azo dyes and the production and use thereof | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |