Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829856 | 0.75 | S1PR4 (0.37) | KDM4EHTT | |
| SCHEMBL31442507 | 0.73 | GSK3A (0.51) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL11243422 | 0.71 | GSK3A (0.50) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL31090336 | 0.69 | MAPT (0.50) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL11613139 | 0.69 | GSK3A (0.44) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL3022499 | 0.69 | GSK3A (0.60) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL9473443 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL9623389 | 0.66 | POLB (0.56) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL11243329 | 0.66 | GSK3A (0.44) | SMN1; SMN2GSK3AGSK3BPOLBMAPT | |
| SCHEMBL23643029 | 0.66 | GSK3A (0.47) | SMN1; SMN2GSK3AGSK3BPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326878-A | Herbicidal and plant-growth-regulating 1,2,4-trisubstituted-1,2,4-triazolidin-3,5-dithiones | CHEVRON RESEARCH (US) | 1982-04-27 | — | — | US | disclosed |
| US-4276420-A | PRE- AND POST-EMERGENCE | CHEVRON RESEARCH COMPANY (US) | 1981-06-30 | — | — | US | disclosed |