Methacrylic Acid

Methacrylic Acid

SCHEMBL11236639

C=C(C)C(=O)O.CCCOCC(O)COC(C)COC(C)COC(C)CO

nearest known ligand 0.47

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.47
HSD17B10 Q99714 1/20 0.39
USP2 O75604 2/20 0.36
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ALOX15 P16050 1/20 0.34
PLA2G2C Q5R387 1/20 0.33
LPAR5 Q9H1C0 1/20 0.32
MAPT P10636 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL11252894 1.00 TDP1 (0.47) TDP1HSD17B10USP2KDM4EALDH1A1
Methacrylic Acid SCHEMBL11240656 0.97 TDP1 (0.46) TDP1HSD17B10USP2KDM4EALDH1A1
Methacrylic Acid SCHEMBL11235433 0.93 USP2 (0.43) TDP1HSD17B10USP2KDM4EALDH1A1
Methacrylic Acid SCHEMBL11111870 0.93 USP2 (0.43) TDP1HSD17B10USP2KDM4EALDH1A1
Methacrylic Acid SCHEMBL11760428 0.91 USP2 (0.51) TDP1USP2KDM4EALDH1A1ALOX15
Methacrylic Acid SCHEMBL11248702 0.90 USP2 (0.45) TDP1HSD17B10USP2KDM4EALDH1A1
Methacrylic Acid SCHEMBL8850668 0.90 TDP1 (0.35) TDP1
Methacrylic Acid SCHEMBL11245493 0.90 TDP1 (0.35) TDP1
Methacrylic Acid SCHEMBL8851502 0.90 TDP1 (0.35) TDP1
Methacrylic Acid SCHEMBL8850652 0.90 TDP1 (0.35) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4310397-A SUSTAINED RELEASE; PREPARED BY IRRADIATION POLYMERIZATION JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JP) 1982-01-12 US disclosed