Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11228943 | 0.83 | EGFR (0.52) | EGFRAPPHTR1AHTR2CHTR2A | |
| SCHEMBL9987719 | 0.82 | EGFR (0.56) | EGFRAPP | |
| SCHEMBL9987722 | 0.82 | EGFR (0.56) | EGFRAPP | |
| SCHEMBL11237104 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP | |
| SCHEMBL11238128 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP | |
| SCHEMBL11240642 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP | |
| SCHEMBL11240644 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP | |
| SCHEMBL11240157 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP | |
| SCHEMBL11239779 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP | |
| SCHEMBL11249500 | 0.79 | EGFR (0.56) | EGFRAPPALDH1A1SMN1; SMN2SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |