Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.64 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | STK39 | Q9UEW8 | 10/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | PNLIP | P16233 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365367 | 0.86 | AKR1C4 (0.62) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL19321444 | 0.84 | AKR1C4 (0.60) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL3713890 | 0.84 | AKR1C4 (0.60) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL6714042 | 0.82 | AKR1C4 (0.58) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL13320226 | 0.81 | AKR1C4 (0.56) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL28392557 | 0.81 | HSPA5 (0.64) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL19325836 | 0.80 | AKR1C4 (0.55) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL2454782 | 0.80 | AKR1C4 (0.55) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL29375230 | 0.78 | AKR1C2 (1.00) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 | |
| SCHEMBL184603 | 0.78 | AKR1C2 (1.00) | AKR1C4AKR1C3AKR1C2AKR1C1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324682-A | PRESSURE RUPTURABLE; FOR MARKING AND IDENTIFICATION | AMERICAN CYANAMID COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-3994987-A | Metal deactivators as adhesion promotors for vulcanizable elastomers to metals | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
| US-3960755-A | Detecting compositions and method of using same | AMERICAN CYANAMID COMPANY (US) | 1976-06-01 | — | — | US | disclosed |