SCHEMBL11237495

SCHEMBL11237495

CC1=CC(=O)C(C(O)C(C)C)=CC1=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 2/20 0.63
PLK2 Q9NYY3 2/20 0.63
EEF2K O00418 1/20 0.63
STAT3 P40763 1/20 0.35
MAPK1 P28482 4/20 0.34
ALDH1A1 P00352 4/20 0.34
LMNA P02545 3/20 0.34
MEN1 O00255 3/20 0.34
GAA P10253 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPT P10636 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
USP2 O75604 2/20 0.32
BLM P54132 2/20 0.32
PLIN1 O60240 1/20 0.32
NR1I2 O75469 1/20 0.32
GSR P00390 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10447078 0.83 PLK1 (0.68) PLK1PLK2EEF2KSTAT3MAPK1
Thymoquinone SCHEMBL542535 0.78 PLK1 (1.00) PLK1PLK2EEF2KSTAT3MAPK1
Thymoquinone SCHEMBL17499955 0.76 PLK1 (0.95) PLK1PLK2EEF2KSTAT3MAPK1
SCHEMBL10446164 0.73 EEF2K (0.55) PLK1PLK2EEF2KSTAT3MAPK1
SCHEMBL10446744 0.72 PLK1 (0.65) PLK1PLK2EEF2KSTAT3MAPK1
SCHEMBL11244829 0.71 PLK1 (0.63) PLK1PLK2EEF2KSTAT3MAPK1
P-Xyloquinone SCHEMBL49964 0.71 PLK1 (0.60) PLK1PLK2EEF2KSTAT3MAPK1
SCHEMBL10446702 0.71 PLK1 (0.57) PLK1PLK2EEF2KSTAT3MAPK1
SCHEMBL10492517 0.70 PLK1 (0.50) PLK1PLK2EEF2KMAPK1ALDH1A1
SCHEMBL8393515 0.67 EEF2K (0.52) PLK1PLK2EEF2KSTAT3MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4324852-A REDOX COUPLES EASTMAN KODAK COMPANY (US) 1982-04-13 US claimed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US claimed
US-4195998-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, QUINONE OR CARBAZIDE PHOTOREDUCTANT EASTMAN KODAK COMPANY (US) 1980-04-01 US claimed
US-4332884-A USING A DIOXIME CHELATING AGENT RICOH CO., LTD. (JP) 1982-06-01 US disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed
US-4306014-A AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM RICOH CO., LTD. (JP) 1981-12-15 US disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed