Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237897 | 1.00 | KDM4E (0.48) | KDM4EALDH1A1TSHRCYP19A1ESR1 | |
| SCHEMBL11228296 | 0.88 | HTT (0.53) | KDM4EALDH1A1CYP19A1ESR1ESR2 | |
| SCHEMBL11223244 | 0.88 | CYP19A1 (0.40) | KDM4EALDH1A1TSHRCYP19A1ESR1 | |
| SCHEMBL11237695 | 0.87 | CYP19A1 (0.56) | KDM4ECYP19A1ESR1ESR2MAPT | |
| SCHEMBL9790084 | 0.87 | CYP19A1 (0.56) | KDM4ECYP19A1ESR1ESR2MAPT | |
| SCHEMBL9790080 | 0.87 | CYP19A1 (0.56) | KDM4ECYP19A1ESR1ESR2MAPT | |
| Water SCHEMBL10651421 | 0.86 | CYP19A1 (0.55) | KDM4ECYP19A1ESR1ESR2MAPT | |
| SCHEMBL11222475 | 0.85 | CYP19A1 (0.49) | KDM4EALDH1A1CYP19A1MAPTLMNA | |
| SCHEMBL11222473 | 0.85 | CYP19A1 (0.49) | KDM4EALDH1A1CYP19A1MAPTLMNA | |
| SCHEMBL11231210 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1CYP19A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357338-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-11-02 | — | — | US | disclosed |
| US-4309434-A | Combating fungi with 1-(2-chlorophenyl)-1-(2-chlorobenzyloximino)-2-(1,2,4-triazol-1-yl)-ethane | BAYER AKTIENGESELLSCHAFT (DE) | 1982-01-05 | — | — | US | disclosed |
| EP-0004917-B1 | OXIMINO-TRIAZOLYL ETHANES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1981-05-13 | — | — | EP | disclosed |
| US-4264772-A | Combating fungi with 1-phenyl-1-oximino-2-(1,2,4-triazol-1-yl)-ethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-28 | — | — | US | disclosed |
| EP-0004917-A1 | Oximino-triazolyl ethanes, process for their preparation and their use as fungicides | BAYER AG (DE) | 1979-10-31 | — | — | EP | disclosed |