SCHEMBL1123792

SCHEMBL1123792

NC(N)CCC[C@H](N)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSR P00390 2/20 0.62
ARG2 P78540 4/20 0.56
ARG1 P05089 3/20 0.56
CYP1A2 P05177 3/20 0.54
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29851717 1.00 GSR (0.62) GSRARG2ARG1CYP1A2GRM8
SCHEMBL27471379 1.00 GSR (0.62) GSRARG2ARG1CYP1A2GRM8
SCHEMBL8234491 0.95 GSR (0.70) GSRARG2ARG1CYP1A2GRM8
SCHEMBL10135848 0.92 GSR (0.71) GSRARG2ARG1CYP1A2GRM8
SCHEMBL29387596 0.92 GSR (0.71) GSRARG2ARG1CYP1A2GRM8
SCHEMBL15987065 0.92 GSR (0.71) GSRARG2ARG1CYP1A2GRM8
SCHEMBL17323357 0.92 GSR (0.71) GSRARG2ARG1CYP1A2GRM8
SCHEMBL29289 0.92 GSR (0.71) GSRARG2ARG1CYP1A2GRM8
SCHEMBL29291 0.92 GSR (0.71) GSRARG2ARG1CYP1A2GRM8
SCHEMBL21689907 0.86 GSR (0.80) GSRARG2ARG1CYP1A2GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116390938-A Exendin-4 analogues TXP制药股份有限公司 2023-07-04 CN claimed
CN-119451988-B Anti-B7-H3 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2025-06-03 CN disclosed
CN-119894929-A Cancer treatment using PD-1 or PD-L1 inhibitors and antibody drug conjugates targeting Claudin 18.2 礼新医药科技(上海)有限公司 2025-04-25 CN disclosed
CN-118994403-B Anti-glypican 3 antibodies 乐普创一生物科技(上海)有限公司 2025-04-01 CN disclosed
CN-119470884-A Pharmacokinetic immunoassay for inhibiting interference 豪夫迈·罗氏有限公司 2025-02-18 CN disclosed
CN-119451988-A Anti-B7-H3 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2025-02-14 CN disclosed
CN-119080937-A Anti-glypican 3 antibodies 乐普创一生物科技(上海)有限公司 2024-12-06 CN disclosed
CN-118994403-A Anti-glypican 3 antibodies 乐普创一生物科技(上海)有限公司 2024-11-22 CN disclosed
CN-118946590-A Anti-5T 4 antibodies and uses thereof 乐普创一生物科技(上海)有限公司 2024-11-12 CN disclosed
CN-118891273-A Annexin A1 derived polypeptide analogs 雷索特制药股份有限公司 2024-11-01 CN disclosed
US-6583266-B1 Peptide for use in the diagnosis and treatment of skin disorders and tuberculosis GENOME THERAPEUTICS CORPORATION 2003-06-24 US disclosed
US-20020197704-A1 Nucleic acid molecule, comprising a nucleic acid coding for a polypeptide with chorismate mutase activity RHEIN BIOTECH GESELLSCHAFT FUR NEUE BIOTECHNOLOGISHE PROZESSE UND PRODUKTE MBH (DE) 2002-12-26 US disclosed
US-20020177551-A1 Compositions and methods for treatment of neoplastic disease TERMAN DAVID S (US) 2002-11-28 US disclosed
US-6458589-B1 CULTURED IN PRESENCE OF DIFFERENTIATION AGENT; DRUG SCREENING; REGENERATING LIVER FUNCTION GERON CORPORATION 2002-10-01 US disclosed
EP-0772628-B1 PEPTIDE DERIVED RADIONUCLIDE CHELATORS RESOLUTION PHARM INC (CA) 2000-07-19 EP disclosed
US-5976495-A Peptide derived radionuclide chelators RESOLUTION PHARMACEUTICALS, INC. (CA) 1999-11-02 US disclosed
EP-0606411-B1 NOVEL COMPOUNDS AND CONJUGATES BEHRING DIAGNOSTICS INC (US) 1999-03-03 EP disclosed
US-5780006-A RADIOLABELED TRIPEPTIDE COMPLEX CONJUGATED TO OLIGO- OR POLYPEPTIDE TARGETING AGENT; MEDICAL DIAGNOSIS RESOLUTION PHARMACEUTICALS INC. (CA) 1998-07-14 US disclosed
US-5662885-A FOR USE IN IMAGING SITES OF DIAGNOSTIC INTEREST RESOLUTION PHARMACEUTICALS INC. (CA) 1997-09-02 US disclosed
US-5294536-A Immunoassay using a solid support having a protein linked to a solid support by a carbamic acid-containing maleiimide PB DIAGNOSTIC SYSTEMS, INC. (US) 1994-03-15 US disclosed