Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.60 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476950 | 0.79 | ALPG (0.58) | CYP19A1CYP11B1CYP11B2CA12 | |
| SCHEMBL10878611 | 0.77 | CA12 (0.56) | CYP19A1CYP11B1CYP11B2CA12 | |
| SCHEMBL11228752 | 0.77 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL18788080 | 0.77 | CYP19A1 (0.52) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11230081 | 0.77 | CYP11B1 (0.53) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11276476 | 0.75 | POLB (0.55) | CYP19A1 | |
| SCHEMBL11275825 | 0.75 | CYP11B1 (0.55) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL5730977 | 0.75 | CYP19A1 (1.00) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8144459 | 0.74 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2CA12 | |
| SCHEMBL11705310 | 0.74 | CYP11B1 (0.56) | CYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |