Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17100040 | 1.00 | TSHR (0.56) | TSHRSMPD1CES2FAAHPLA2G2C | |
| SCHEMBL28326711 | 0.94 | TSHR (0.56) | TSHRCES2FAAHPLA2G2CNAAA | |
| SCHEMBL28328056 | 0.92 | TSHR (0.53) | TSHRCES2FAAHPLA2G2CNAAA | |
| SCHEMBL28204137 | 0.89 | TSHR (0.57) | TSHRCES2PLA2G2CNAAA | |
| SCHEMBL11232936 | 0.89 | TSHR (0.57) | TSHRCES2PLA2G2CNAAA | |
| SCHEMBL10772767 | 0.89 | TSHR (0.57) | TSHRCES2PLA2G2CNAAA | |
| SCHEMBL6986547 | 0.89 | TSHR (0.55) | TSHRSMPD1FAAHGPR84FFAR1 | |
| SCHEMBL22572596 | 0.89 | TSHR (0.55) | TSHRSMPD1FAAHGPR84FFAR1 | |
| SCHEMBL22572582 | 0.89 | TSHR (0.55) | TSHRSMPD1FAAHGPR84FFAR1 | |
| SCHEMBL22572612 | 0.89 | TSHR (0.55) | TSHRSMPD1FAAHGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357435-A | Novel polymers of alkyl methacrylates | ROHM AND HAAS COMPANY (US) | 1982-11-02 | — | — | US | disclosed |
| US-4336345-A | Composition comprising condensation cross-linkable novel methacrylate polymers | ROHM AND HAAS COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4226753-A | Novel methacrylic polymers having condensation-crosslinkable functionality | ROHM AND HAAS COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-4103093-A | CHAIN REGULATING ALCOHOL, ALKOXIDE CATALYST | ROHM AND HAAS COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
| US-4056559-A | ANIONIC POLYMERIZATION | ROHM AND HAAS COMPANY (US) | 1977-11-01 | — | — | US | disclosed |