⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877619 | 0.95 | — | — | |
| SCHEMBL2398417 | 0.89 | — | — | |
| SCHEMBL1819721 | 0.70 | — | — | |
| SCHEMBL12969947 | 0.69 | — | — | |
| SCHEMBL1848719 | 0.68 | MAPK1 (0.31) | — | |
| SCHEMBL31579237 | 0.67 | — | — | |
| SCHEMBL15848301 | 0.65 | — | — | |
| SCHEMBL8050366 | 0.64 | — | — | |
| SCHEMBL8052424 | 0.63 | — | — | |
| SCHEMBL108199 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937267-A4 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2009-08-26 | — | — | EP | claimed |
| EP-1937267-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-07-02 | — | — | EP | claimed |
| WO-2007016639-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2007-02-08 | — | — | WO | claimed |
| EP-3497100-A1 | CHEMICAL COMPOUNDS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2019-06-19 | — | — | EP | disclosed |
| EP-3414228-A1 | CHEMICAL COMPOUNDS AS INHIBITORS OF KINASE ACTIVITY | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2018-12-19 | — | — | EP | disclosed |
| WO-2018029126-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-02-15 | — | — | WO | disclosed |
| WO-2017137535-A1 | CHEMICAL COMPOUNDS AS INHIBITORS OF KINASE ACTIVITY | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-08-17 | — | — | WO | disclosed |
| EP-3057587-A1 | PI3K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-08-24 | — | — | EP | disclosed |
| EP-3057588-A1 | PI3K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015055690-A1 | PI3K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-04-23 | — | — | WO | disclosed |
| WO-2015055691-A1 | PI3K INHIBITOR FOR TREATMENT OF RESPIRATORY DISEASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-04-23 | — | — | WO | disclosed |
| WO-2009147188-A1 | BENZPYRAZOL DERIVATIVES AS INHIBITORS OF PI3 KINASES | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009147187-A1 | 4-CARBOXAMIDE INDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF P13-KINASES | GLAXO GROUP LIMITED (GB) | 2009-12-10 | — | — | WO | disclosed |
| WO-2009112473-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-09-17 | — | — | WO | disclosed |
| EP-2081910-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043789-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |
| EP-0500653-A4 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST INC (US) | 1995-08-23 | — | — | EP | disclosed |
| EP-0500653-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST PHARMACEUTICALS INC. (US) | 1992-09-02 | — | — | EP | disclosed |
| WO-1991006548-A1 | INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE | BIOCRYST, INC. (US) | 1991-05-16 | — | — | WO | disclosed |
| US-5008265-A | 2-amino-7-(alicyclomethyl)-3H,5H,-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same | BIOCRYST, INC. (US) | 1991-04-16 | — | — | US | disclosed |