Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239889 | 1.00 | POLB (0.58) | POLBHTTNPSR1RAB9ANPC1 | |
| SCHEMBL11239885 | 1.00 | POLB (0.58) | POLBHTTNPSR1RAB9ANPC1 | |
| SCHEMBL19449710 | 0.93 | POLB (0.65) | POLBHTTNPSR1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL17560921 | 0.92 | POLB (0.63) | POLBHTTNPSR1RAB9ANPC1 | |
| SCHEMBL7594903 | 0.86 | MEN1 (0.64) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL21937369 | 0.86 | MEN1 (0.64) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL19449623 | 0.86 | MEN1 (0.64) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL17560801 | 0.84 | MEN1 (0.62) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11695624 | 0.81 | MEN1 (0.58) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11695619 | 0.81 | MEN1 (0.58) | RAB9ANPC1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321274-A | Substituted 1-(cinnamylideneamino)-3-benzyli-deneaminoguanidines active against Giardia lamblia and Trichomonas vaginalis | MERCK & CO., INC. (US) | 1982-03-23 | — | — | US | claimed |
| US-4321274-A | Substituted 1-(cinnamylideneamino)-3-benzyli-deneaminoguanidines active against Giardia lamblia and Trichomonas vaginalis | MERCK & CO., INC. (US) | 1982-03-23 | — | — | US | disclosed |
| US-4321274-A | Substituted 1-(cinnamylideneamino)-3-benzyli-deneaminoguanidines active against Giardia lamblia and Trichomonas vaginalis | MERCK & CO., INC. (US) | 1982-03-23 | — | — | US | disclosed |