Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.51 |
| ▸ | THRA | P10827 | 4/20 | 0.49 |
| ▸ | THRB | P10828 | 4/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.48 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242133 | 0.94 | S1PR1 (0.48) | SPHK1S1PR1THRATHRBFAAH | |
| SCHEMBL11247581 | 0.88 | S1PR1 (0.62) | SPHK1S1PR1THRATHRBFAAH | |
| SCHEMBL11239458 | 0.88 | S1PR1 (0.62) | SPHK1S1PR1THRATHRBFAAH | |
| SCHEMBL11229424 | 0.88 | S1PR1 (0.62) | SPHK1S1PR1THRATHRBFAAH | |
| SCHEMBL11246092 | 0.85 | PRSS1 (0.46) | CA2 | |
| SCHEMBL21523345 | 0.84 | SPHK1 (0.58) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL8656993 | 0.84 | SPHK1 (0.58) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL22346236 | 0.84 | SPHK1 (0.58) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL21523329 | 0.84 | SPHK1 (0.54) | SPHK1S1PR1THRATHRBS1PR3 | |
| SCHEMBL28413635 | 0.84 | SPHK1 (0.58) | SPHK1S1PR1THRATHRBS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348399-A | Antiatherosclerotic and hypolipidemic 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |